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	Name▼ / Code▼	Industry	Offer Price	Lot Size	Entry Fee	Closing Date	Grey Market Date▼	Listing Date▲
	REFIRE 02570.HK	Electrical Components & Equipment	145-165	20	3,333	2024/12/03	2024/12/05	2024/12/06
	Dmall 02586.HK	Application Software	30.21	100	N/A	2024/12/03	2024/12/05	2024/12/06

Summary

We are a biotechnology company based in China and the United States committed to advancing therapies for significant infectious diseases, such as hepatitis B virus (HBV), human immunodeficiency virus (HIV), multi-drug resistant (MDR) or extensive drug resistant (XDR) gram-negative infections, and other illnesses, such as the central nervous system (CNS) diseases, which have significant public health burdens in China and worldwide. We are achieving this vision with a business model combining internal discovery and in-licensing. Since our inception in 2017, under the leadership of our experienced management team with a track record of successfully developing and commercializing products across different geographies, we have built a pipeline of more than ten innovative product candidates that focus on infectious diseases and CNS diseases and range from preclinical to clinical stage programs. We also have options to in-license up to five additional innovative programs from our license partners. The drug candidates in our existing pipeline are primarily focused on infectious diseases and also CNS diseases. Our infectious disease programs include (i) our HBV functional cure treatment (i.e., achievement of HBsAg loss sustained for at least six months after a finite duration of treatment) that uses an HBV-specific B cell and T cell therapeutic vaccine (BRII-179) and an HBV-targeting siRNA (BRII-835), (ii) our once-weekly single tablet regime (QW STR) (BRII-778 and BRII-732) to improve the quality of life of HIV-infected patients, (iii) OMNIvance (BRII-636, our broad spectrum -lactamase inhibitor (BLI), in combination with an IV -lactam antibiotic) and ORAvance (BRII-672, our broad spectrum BLI, in combination with an IV -lactam antibiotic) as well as next-generation polymyxin (BRII-693) for the treatment of MDR/XDR gram-negative bacterial infections, (iv) BRII-658 for the treatment of MDR/XDR tuberculosis (TB) and mycobacterial infections and (v) our cocktail of two fully human noncompeting neutralizing antibodies (BRII-196 and BRII-198) for the treatment of COVID-19. For our CNS disease programs, we are developing BRII-296 to address the challenges associated with current treatments for postpartum depression (PPD) and major depressive disorder (MDD). Source: BRII - B (02137) Prospectus (IPO Date : 2021/06/30)
Listing Market	MAIN
Industry	Biotechnology
Background	Others
Major Business Area	N/A

Corporate Information

Substantial Shareholders	ARCH Venture Partners IX, LLC (12.36%) Boyu Group, LLC (9.85%)
Directors	Zhi HONG (Chairman and Chief Executive Officer and Executive Director) Ankang LI (Chief Financial Officer and Executive Director) Grace Hui TANG (Independent Non-Executive Director) Gregg Huber ALTON (Independent Non-Executive Director) Martin J MURPHY JR (Independent Non-Executive Director) Yiu Wa Alec TSUI (Independent Non-Executive Director) Taiyin Yang (Independent Non-Executive Director)
Company Secretary	Ankang LI Wing Tsz Wendy HO
Principal Bankers	China Merchants Bank Bank of Beijing Bank of China (Hong Kong) Limited First Citizens Bank
Solicitors	O Melveny & Myers LLP Maples and Calder (Hong Kong) LLP Global Law Office
Auditors	Deloitte Touche Tohmatsu
Registered Office	5th Floor, Manulife Place 348 Kwun Tong Road Kowloon Hong Kong
Share Registrars	Tricor Investor Services Ltd. [Tel: (852) 2980-1333]
Share Registrars Tel No	(852) 2980-1333
Internet Address	http://www.briibio.com
Email Address	[email protected]
Tel No
Fax No

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